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2018

Sun, S., Akkapeddi, P., Marques, M.F., Martinez, N., Torres, V.M., Cordeiro, C., Boutureira, O., Bernardes, G. (2018) One-pot stapling of interchain disulfides of antibodies using an isobutylene motif. Organic & Biomolecular Chemistry (accepted, in press). doi: 10.1039/x0xx0000x

Maia, M., Maccelli, A., Nascimento, R., Ferreira, A.E.N., Crestoni, M.E., Cordeiro, C., Figueiredo, A.*, Sousa Silva, M.* (2018) Early detection of Plasmopara viticola infected leaves through FT-ICR-MS metabolic profiling. Acta Horticulturae (accepted, in press)

Osawa R.A., Carvalho A.P., Monteiro O.C., Oliveira M.C., Florêncio M.H. (2018) Transformation products of citalopram: Identification and in-silico toxicological assessment. Chemosphere (In Press, Accepted Manuscript). doi: 10.1016/j.chemosphere.2018.11.027

Laureano, G., Figueiredo, J., Cavaco, A.R., Duarte, B., Caçador, I., Malhó, R., Sousa Silva, M., Matos, A.R., Figueiredo, A. (2018) The interplay between membrane lipids and phospholipase A family members in grapevine resistance against Plasmopara viticola. Scientific Reports 8: 14538. doi: 10.1038/s41598-018-32559-z

Lamy, E., Neves, S., Ferreira, J., Rodrigues, L., da Costa, G., Cordeiro, C., Fialho, L., Lima, M., Costa, A.R., Antunes, C.M., Lopes, O., Amado, F., Capela E Silva F. (2018) Effects of hyperleptinemia in rat saliva composition, histology and ultrastructure of the major salivary glands. Archives of Oral Biology 96: 1-12. doi: 10.1016/j.archoralbio.2018.08.005

Piedade C.A., Sousa Silva M., Cordeiro C., Ferreira A.E.N. (2018) Virus Disassembly Pathways Predicted from Geometry and Configuration Energy. In: Peixoto N., Silveira M., Ali H., Maciel C., van den Broek E. (eds) Biomedical Engineering Systems and Technologies. BIOSTEC 2017. Communications in Computer and Information Science, vol 881. Springer, Cham. doi: 10.1007/978-3-319-94806-5_16

O’Caoimh, R., Molloy, D.W., Fitzgerald, C., Van Velsen, L., Cabrita, M., Nassabi, M.H., de Vette, F., Dekker-van Weering, M., Jansen-Kosterink, S., Kenter, W., Frazer, S., Rauter, A.P., Turkman, A., Antunes, M., Turkman, F., Silva, M.S., Martins, A., Costa, H.S., Albuquerque, T.G., Ferreira, A., Scherillo, M., De Luca, V., Illario, M., García A., Sanchez Carrion, R., Gómez Aguilera, E.J., Solana Sánchez, J., Hermans, H., Vollenbroek-Hutten, M. (2018) ICT-Supported Interventions Targeting Pre-frailty: Healthcare Recommendations from the Personalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) Study. In: Röcker C., O’Donoghue J., Ziefle M., Maciaszek L., Molloy W. (eds) Information and Communication Technologies for Ageing Well and e-Health. ICT4AWE 2017. Communications in Computer and Information Science, vol 869. Springer, Cham. doi: 10.1007/978-3-319-93644-4_4

Maia, M., Ferreira, A.E.N., Marques, A.P., Figueiredo, J., Ponces Freire, A., Cordeiro, C., Figueiredo, A.*, Sousa Silva, M.* (2018) Uncovering markers for downy mildew resistance in grapevine through mass spectrometry-based metabolomics. Revista de Ciências Agrárias (in press). doi: 10.19084/RCA17334 

Figueiredo, A., Figueiredo, J., Maia, M., Cavaco, A.R., Laureano, G., Nascimento, R., da Silva, C., Matos, A.R., Sousa Silva, M. (2018) Grapevine-downy mildew resistance strategies: towards a sustainable viticulture. Revista de Ciências Agrárias (in press). DOI: 10.19084/RCA17325 

Figueiredo, J., Laureano, G., da Silva, C., Maia, M., Sousa Silva, M.*, Figueiredo, A.* (2018) Assessing the link between subtilases and lipid signaling events in grapevine downy mildew resistance. Revista de Ciências Agrárias (in press). DOI: 10.19084/RCA17330

Figueiredo, J., Sousa Silva, M.*, Figueiredo, A.* (2018) Subtilisin-like proteases in plant defence: the past, the present and beyond. Molecular Plant Pathology 19: 1017–1028. doi: 10.1111/mpp.12567

Henriques J., Falé P., Pacheco R., Florêncio M.H., Serralheiro M.L. (2018) Phenolic compounds from Actinidia deliciosa leaves: Caco-2 permeability, enzyme inhibitory activity and cell protein profile studies. Journal of King Saud University – Science 30: 513-518. doi: 10.1016/j.jksus.2017.07.007

2017

Rodrigues, L., da Costa, G., Cordeiro, C., Pinheiro, C.C., Amado, F., Lamy, E. (2017) Relationship between saliva protein composition and 6-n-Propylthiouracil bitter taste responsiveness in young adults. Journal of Sensory Studies 32(4): Article nr e12275- doi: 10.1111/joss.12275

Figueiredo, J., Maia, M., Sousa Silva, M.*, Figueiredo, A.* (2017) Grapevine subtilase family: update on new sequences and nomenclature proposal. Frontiers in Plant Science 8: 716. doi: 10.3389/fpls.2017.00716

Piedade C., Ferreira A. and Cordeiro C. (2017). How to Disassemble a Virus Capsid – A Computational Approach. In: Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies – Volume 3: BIOINFORMATICS, (BIOSTEC 2017), 217-222. ISBN: 978-989-758-214-1. doi: 10.5220/0006249802170222

O’Caoimh, R., Molloy, D.W., Fitzgerald, C., Van Velsen, L., Cabrita, M., Nassabi, M.H., de Vette, F., Dekker-van Weering, M., Jansen-Kosterink, S., Kenter, W., Frazer, S., Rauter, A.P., Turkman, A., Antunes, M., Turkman, F., Silva, M.S., Martins, A., Costa, H.S., Albuquerque, T.G., Ferreira, A., Scherillo, M., De Luca, V., Illario, M., García A., Sanchez Carrion, R., Gómez Aguilera, E.J., Solana Sánchez, J., Hermans, H., Vollenbroek-Hutten, M. (2017) Healthcare Recommendations from the PERsonalised ICT Supported Service for Independent Living and Active Ageing (PERSSILAA) study. (Conference Paper) In: Proceedings of the 3rd International Conference on Information and Communication Technologies for Ageing Well and e-Health (ICT4AWE 2017), 91-103. ISBN: 978-989-758-251-6

Vicente Miranda H, Szego ÉM, Oliveira LM, Breda C, Darendelioglu E, de Oliveira RM, Ferreira DG, Gomes MA, Rott R, Oliveira M, Munari F, Enguita FJ, Simões T, Rodrigues EF, Heinrich M, Martins IC, Zamolo I, Riess O, Cordeiro C, Ponces-Freire A, Lashuel HA, Santos NC, Lopes LV, Xiang W, Jovin TM, Penque D, Engelender S, Zweckstetter M, Klucken J, Giorgini F, Quintas A, Outeiro TF (2017) Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies. Brain 140(5): 1399-1419. doi: 10.1093/brain/awx056

Henriques J., Ribeiro M.J., Falé P.L., Pacheco R., Ascenção L., Florêncio M.H., Serralheiro M.L.M. (2017) Valorization of kiwifruit production: leaves of the pruning branches of Actinidia deliciosa as a promising source of polyphenols. Eur Food Res Technol 243: 1343–1353. doi: 10.1007/s00217-017-2845-y

Rodrigues A.M., Ciriani L., Silva P.V.L., Falé P., Teixeira V., Madeira P., Machuqueiro M., Pacheco R., Florêncio M.H., Ascensão L., Serralheiro M.L,M,, (2017) Antiacetylcholinesterase activity and docking studies with chlorogenic acid, cynarin and arzanol from Helichrysun italicum subsp picardii and H. stoechas. Medicinal Chemistry Research, 26: 2942–2950. doi: 10.1007/s00044-017-1994-7

Jorge T.F., Florêncio M.H., Ribeiro-Barros A.I., António C. (2017) Quantification and structural characterization of raffinose familyoligosaccharides in Casuarina glauca plant tissues by porous graphiticcarbon electrospray quadrupole ion trap mass spectrometry, International Journal of Mass Spectrometry 413:127–134 doi: 10.1016/j.ijms.2016.05.004

2016

Figueiredo, J., Costa, G., Maia, M., Paulo, O., Malhó, R., Sousa Silva, M.*, Figueiredo, A.* (2016) Revisiting Vitis vinífera subtilase gene family: a possible role in grapevine resistance against Plasmopara viticola. Frontiers in Plant Science 7: 1783. doi: 10.3389/fpls.2016.01783

Guerreiro, A., Figueiredo, J., Sousa Silva, M.*, Figueiredo, A.* (2016) Linking jasmonic acid to grapevine resistance against the biotrophic oomycete Plasmopara viticola. Frontiers in Plant Science – Special Research Topic on “Biotrophic plant-microbe interactions” 7, 565. doi: 10.3389/fpls.2016.00565

Maia, M., Monteiro, F., Sebastiana, M., Marques, A.P., Ferreira, A.E.N., Ponces Freire, A., Cordeiro, C., Figueiredo, A.*, Sousa Silva, M.* (2016) Metabolite extraction for high-throughput FTICR-MS-based metabolomics in grapevine. EuPA Open Proteomics 12: 4-9. doi: 10.1016/j.euprot.2016.03.002

Fonseca, D, Gilberto, S., Ribeiro-Silva, C., Ribeiro, R., Guinote, I.B., Saraiva, S., Gomes, R.A., Mateus, E., Viana, A., Barroso, E., Freire, A.P., Freire, P., Cordeiro, C., Da Costa, G. (2016) The role of fibrinogen glycation in ATTR: Evidence for chaperone activity loss in disease. Biochemical Journal 473, 2225-2237

Lebesgue N, da Costa G, Ribeiro RM, Ribeiro-Silva C, Martins GG, Matranga V, Scholten A, Cordeiro C, Heck AJ, Santos R. (2016) Deciphering the molecular mechanisms underlying sea urchin reversible adhesion: A quantitative proteomics approach. Journal of Proteomics 138, 61-71. doi: 10.1016/j.jprot.2016.02.026

Lebesgue N., da Costa G., Ribeiro R.M., Ribeiro-Silva C., Martins G.G., Matranga V., Scholten A., Cordeiro C., Heck A.J., Santos R. (2016) Proteomic dataset of the sea urchin Paracentrotus lividus adhesive organs and secreted adhesive. Data Brief. 7: 1497-505. doi: 10.1016/j.dib.2016.04.002

Toubarro D., Gouveia A., Ribeiro R.M., Simões N., da Costa G., Cordeiro C., Santos R. (2016) Cloning, Characterization, and Expression Levels of the Nectin Gene from the Tube Feet of the Sea Urchin Paracentrotus lividus. Marine Biotechnology (NY). 18(3): 372-83. doi: 10.1007/s10126-016-9698-4

Vilas-Boas F, Bagulho A, Tenente R, Teixeira VH, Martins G, da Costa G, Jerónimo A, Cordeiro C, Machuqueiro M, Real C. (2016) Hydrogen peroxide regulates cell adhesion through the redox sensor RPSA. Free Radic Biol Med. 90, 145-57. doi: 10.1016/j.freeradbiomed.2015.11.019. (Epub 2015, Nov 18)

Marques A.P., Serralheiro M.L., Ferreira A.E., Freire A.P., Cordeiro C., Sousa Silva M. (2016) Metabolomics for undergraduates: Identification and pathway assignment of mitochondrial metabolites. Biochem Mol Biol Educ. 44(1), 38-54. doi: 10.1002/bmb.20919. (Epub 2015, Nov 5)

Saraiva M.A, Borges C.M., Florêncio M.H. (2016) Mass spectrometric studies of the reaction of a blocked arginine with diketonic α-dicarbonyls, Amino acids, 48:873–885. doi:10.1007/s00726-015-2135-6

2015

Oliveira BL, Morais M, Mendes F, Moreira IS, Cordeiro C, Fernandes PA, Ramos MJ, Alberto R, Santos I, Correia JD. (2015) Re(I) and Tc(I) complexes for targeting nitric oxide synthase: influence of the chelator in the affinity for the enzyme. Chem Biol Drug Des. 86(5), 1072-86. doi: 10.1111/cbdd.12575

Gaspar H, Bronze S, Ciríaco S, Queirós CR, Matias A, Rodrigues J, Oliveira C, Cordeiro C, Santos S. (2015) 4F-PBP (4′-fluoro-α-pyrrolidinobutyrophenone), a new substance of abuse: Structural characterization and purity NMR profiling. Forensic Sci Int. 252, 168-76. doi: 10.1016/j.forsciint.2015.05.003

Cal PM, Frade RF, Cordeiro C, Gois PM. (2015) Reversible lysine modification on proteins by using functionalized boronic acids. Chemistry 21(22),8182-7. doi: 10.1002/chem.201500127

da Costa G, Ribeiro-Silva C, Ribeiro R, Gilberto S, Gomes RA, Ferreira A, Mateus É, Barroso E, Coelho AV, Freire AP, Cordeiro C. (2015) Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease. PLoS One 10(7), e0125392. doi: 10.1371/journal.pone.0125392

Cachatra, V., Almeida, A., Sardinha, J., Lucas, S.D., Gomes, A., Vaz, P.D., Florencio, M.H., Nunes, R., Vila-Vicosa, D., Calhorda, M.J., et al. (2015) Wittig Reaction: Domino Olefination and Stereoselectivity DFT Study. Synthesis of the Miharamycins' Bicyclic Sugar Moiety. Organic Letters 17, 5622-5625. doi: 10.1021/acs.orglett.5b02849 

2014

Cardoso LS, Suissas CE, Ramirez M, Antunes M, Pinto FR (2014) Comparison of alternative mixture model methods to analyze bacterial CGH experiments with multi-genome arrays. BMC Res Notes., 7, 148

Simões RG, Diogo HP, Dias A, Oliveira MC, Cordeiro C, Bernardes CE, Minas Da Piedade ME. (2014) Thermal stability of simvastatin under different atmospheres. J Pharm Sci., 103, 241-248

Cal PM, Frade RF, Chudasama V, Cordeiro C, Caddick S, Gois PM. (2014) Targeting cancer cells with folic acid-iminoboronate fluorescent conjugates. Chem Commun (Camb) 50, 5261-5263 

Teixeira, B., Fidalgo, L., Mendes, R., Costa, G., Cordeiro, C., Marques, A., Saraiva, J.A., Nunes, M.L. (2014) Effect of high pressure processing in the quality of sea bass (Dicentrarchus labrax) fillets: Pressurization rate, pressure level and holding time. Journal of Innovative Food Science and Emerging Technologies, 22, 31-39 

Trübenbach K, da Costa G, Ribeiro-Silva C, Mesquita Ribeiro R, Cordeiro C, Rosa R (2014) Hypoxia-driven selective degradation of cellular proteins in jumbo squids during diel migration to the oxygen minimum zones. Marine Biology, 161, 575-584 

Carrolo M, Pinto FR, Melo-Cristino J, Ramirez M. (2014) Pherotype influences biofilm growth and recombination in Streptococcus pneumoniae. PLoS One. 2014 Mar 19;9(3):e92138. doi: 10.1371/journal.pone.0092138

Figueiredo N.L., Falé P.L., Madeira P.J.A., Florêncio M.H., Ascensão L., Serralheiro M.L.M., Lino A.R (2014) Phytochemical Analysis of Plectranthus sp. Extracts and Application in Inhibition of Dental Bacteria, Streptococcus sobrinus and Streptococcus mutans. European Journal of Medicinal Plants 4: 794-809. doi: 10.9734/EJMP/2014/7544 

2013

Sousa Silva, M., Gomes, R.A., Ferreira, A.E.N., Ponces Freire, A., Cordeiro, C. (2013) The glyoxalase pathway: The first hundred years… and beyond. Biochemical Journal 453(1): 1-15 (Invited review). DOI: 10.1042/BJ20121743

Meireles, C., Costa, G., Guinote, I., Albuquerque, T., Botelho, A., Cordeiro, C., Freire, P. (2013) Pseudomonas putida are environmental reservoirs of antimicrobial resistance to β-lactamic antibiotics. World Journal Microbiology Biotechnology Feb 19. [Epub ahead of print]. DOI: 10.1007/s11274-013-1295-3

Teixeira, B.,Fidalgo, L., Mendes, R., Costa, G., Cordeiro, C., Marques, A., Saraiva, J.A., Nunes, M.L. (2013) Changes of Enzymes Activity and Protein Profiles Caused by High-Pressure Processing in Sea Bass (Dicentrarchus labrax) Fillets. Journal of Agricultural and Food Chemistry 61(11), 2851-2860. DOI: 10.1021/jf3049643 

Martins, A., Santos, M.S., Dias, C., Serra, P., Cachatra, V., Pais, J., Caio, J., Teixeira, V.H., Machuqueiro, M., Silva, M.S., Pelerito, A., Justino, J., Goulart, M., Silva, F.V., Rauter, A.P. (2013) Tuning bioactivity of new tensioactive deoxy glycosides with structure: antibacterial activity vs. selective cholinesterase inhibition rationalized by molecular docking. European Journal of Organic Chemistry 2013(8), 1448-1459. (Special issue dedicated to the centenary of the Portuguese Society of Chemistry – SPQ). DOI: 10.1002/ejoc.201201520

Rivaldi, J.D., Sousa Silva, M., Duarte, L.C., Ferreira, A.E.N., Cordeiro, C., Felipe, M.G.A., Ponces Freire, A., Mancilha, I.M. (2013) Metabolism of biodiesel-derived glycerol in probiotic Lactobacillus strains. Applied Microbiology and Biotechnology. 97(4), 1735-1743. DOI: 10.1007/s00253-012-4621-z

Marcelo F., Dias C., Martins A., Madeira P.J., Florêncio M.H., Cañada F.J., Cabrita E.J., Jiménez-Barbero J., Rauter A.P. (2013) Molecular Recognition of Rosmarinic Acid from Salvia sclareoides Extracts by Acetylcholinesterase. A New Binding Site Detected by NMR, Chemistry A. European Journal, 19: 6641–6649. doi: 10.1002/chem.201203966

Madeira P.J.A., Vaz P.D., Bettencourt da Silva R.J.N., Florêncio M.H., (2013) Can semi empirical calculations help solve mass spectrometry problems? Protonation sites and proton affinities of aminoacids, ChemPlusChem 78: 1149 – 1156. doi:
10.1002/cplu.201300173.

Dinis P.C., Falé P.L., Madeira P.J.A., Florêncio, M.H., Serralheiro, M.L.M. (2013) Acetylcholinesterase Inhibitory Activity After in vitro Gastrointestinal Digestion of Infusions of Mentha Species, European Journal of Medicinal Plants, 3: 381-393. doi: 10.9734/EJMP/2013/3430

Falé P.L., Ferreira C., Rodrigues A.M., Cleto P., Madeira P.J.A., Florêncio M.H., Frazão F.N., Serralheiro M.L.M. (2013) Antioxidant and anti-acetylcholinesterase activity of commercially available medicinal infusions after in vitro gastrointestinal digestion, Journal Medicinal Plant Research, 7: 1370-1378.  doi: 10.5897/JMPR13.4438  

2012

Lages, N.F., Cordeiro, C., Sousa Silva, M., Ponces Freire, A., Ferreira, A.E.N. (2012) Optimization of time-course experiments for kinetic model discrimination. PLoS One, 7(3), e32749, DOI: 10.1371/journal.pone.0032749

Falé, P.L., Amaral, F., Madeira, P.J.A., Sousa Silva, M., Florêncio, M.H., Frazão, F.N., Serralheiro, M.L.M. (2012) Acetylcholinesterase inhibition, antioxidant activity and toxicity of Peumus boldus water extracts on HeLa and Caco-2 cell lines. Food and Chemical Toxicology 50(8), 2656-2662, DOI: 10.1016/j.fct.2012.04.049

Sousa Silva, M., Ferreira, A., Gomes, R., Tomás, A., Ponces Freire, A., Cordeiro, C. (2012) The glyoxalase pathway in protozoan parasites. International Journal of Medical Microbiology, 302 (4-5), 225-229 – Special issue “Molecular Principles of Parasitism” (Invited review). DOI: 10.1016/j.ijmm.2012.07.005

Gomes, R.A., Franco, C., Da Costa, G., Planchon, S., Renaut, J., Pinto, F., Sousa Silva, M., Coelho, A.V., Ponces Freire, A., Cordeiro, C. (2012) The proteome response to amyloid protein expression in vivo. PLoS One, 7(11): e50123. DOI:10.1371/journal.pone.0050123

Da Silva, J.P., Kulasekharan, R., Cordeiro, C., Jockusch, S., Turro, N.J., Ramamurthy, V. (2012) Capsular Complexes of Nonpolar Guests with Octa Amine Host Detected in the Gas Phase. Organic Letters. 14(2), 560-563. DOI: 10.1021/ol203139v

Guerreiro, A., da Costa, G., Gomes, R.A., Ribeiro-Silva, C., Gilberto, S., Mateus, E., Monteiro, E., Barroso, E., Coelho, A.V., Freire, A.P., Cordeiro, C. (2012) alpha-Synuclein aggregation in the saliva of familial transthyretin amyloidosis: a potential biomarker. Amyloid, 19(2), 74-80

Cal, P.M., Vicente, J.B., Pires, E., Coelho, A.V., Veiros, L.F., Cordeiro, C., Gois, P.M. (2012) Iminoboronates: a new strategy for reversible protein modification. Journal of the American Chemical Society, 134 (24), 10299-305. DOI: 10.1021/ja303436y

Friães, A., Pinto, F.R., Silva-Costa, C., Ramirez, M., Melo-Cristino, J. (2012) Group A streptococci clones associated with invasive infections and pharyngitis in Portugal present differences in emm types, superantigen gene content and antimicrobial resistance. BMC Microbiology, 12(1), 280

Friães, A., Pinto, F.R., Silva-Costa, C., Ramirez, M., Melo-Cristino, J. (2012) Superantigen gene complement of Streptococcus pyogenes-relationship with other typing methods and short-term stability. European Journal of Clinical Microbiology and Infectious Diseases. E-pub August 2012. DOI: 10.1007/s10096-012-1726-3

Valente, C., Hinds, J., Pinto, F., Brugger, S.D., Gould, K., Muhlemann, K., de Lencastre, H., Sa-Leao, R. (2012) Decrease in Pneumococcal Co-Colonization following Vaccination with the Seven-Valent Pneumococcal Conjugate Vaccine. PLoS One , 7(1), e30235. DOI: 10.1371/journal.pone.0030235

Tendeiro, R., Foxall, R.B., Baptista, A.P., Pinto, F., Soares, R.S., Cavaleiro, R., Valadas, E., Gomes, P., Victorino, R.M.M., Sousa, A.E. (2012) PD-1 and its ligand PD-L1 are progressively up-regulated on CD4 and CD8 T-cells in HIV-2 infection irrespective of the presence of viremia. AIDS, 26(9), 1065-1071. DOI: 10.1097/QAD.0b013e32835374db

Faria, D., Schlicker, A., Pesquita, C., Bastos, H., Ferreira, A.E., Albrecht, M., Falcão, A.O. (2012) Mining GO annotations for improving annotation consistency. PLoS One, 7(7), e40519. DOI: 10.1371/journal.pone.0040519

Madeira P.J.A., Florêncio M.H. (2012) Applications of Tandem Mass Spectrometry: From Structural Analysis to Fundamental Studies, in Tandem Mass Spectrometry - Applications and Principles, Ed. Jeevan K. Prasain, Intech.

Falé P. L., Amaral F., Madeira P.J.A, Sousa Silva M., Florêncio M.H., Frazão F.N., Serralheiro M.L.M. (2012) Acetylcholinesterase inhibition, antioxidant activity and toxicity of Peumus boldus water extracts on HeLa and Caco-2 cell lines, Food Chemistry and Toxicology, 50: 2656–2662. doi: 10.1016/j.fct.2012.04.049

Saraiva M.A., Borges C.M., Florêncio M.H. (2012) Reactions of aminoguanidine with α-dicarbonyl compounds studied by electrospray ionization mass spectrometry, European Journal of Mass Spectrometry, 18: 385-97. doi: 10.1255/ejms.1191

2011

Da Silva JP, Kulasekharan R, Cordeiro C, Jockusch S, Turro NJ, Ramamurthy V (2011) Capsular Complexes of Nonpolar Guests with Octa Amine Host Detected in the Gas Phase. Org Lett. 2011 Dec 23. [Epub ahead of print]

Severiano A, Pinto FR, Ramirez M, Carriço JA (2011) Adjusted Wallace coefficient as a measure of congruence between typing methods. J Clin Microbiol. 49(11), 3997-4000.

Severiano A, Carriço JA, Robinson DA, Ramirez M, Pinto FR (2011) Evaluation of jackknife and bootstrap for defining confidence intervals for pairwise agreement measures. PLoS One 6(5), e19539. DOI:10.1371/journal.pone.0019539

da Costa G, Gomes RA, Guerreiro A, Mateus É, Monteiro E, Barroso E, Coelho AV, Freire AP, Cordeiro C (2011) Beyond genetic factors in familial amyloidotic polyneuropathy: protein glycation and the loss of fibrinogen’s chaperone activity. PLoS One 6(10), e24850. doi:10.1371/journal.pone.0024850

Ribeiro-Silva C, Gilberto S, Gomes RA, Mateus É, Monteiro E, Barroso E, Coelho AV, da Costa G, Freire AP, Cordeiro C (2011) The relative amounts of plasma transthyretin forms in familial transthyretin amyloidosis: a quantitative analysis by Fourier transform ion-cyclotron resonance mass spectrometry. Amyloid 18(4), 191-9.

Barata L, Sousa Silva M, Schuldt L, Ferreira AEN, Gomes RA, Tomás AM, Weiss MS, Ponces Freire A, Cordeiro C (2011) Enlightening the molecular basis of trypanothione specificity in trypanosomatids: mutagenesis of Leishmania infantum glyoxalase II. Experimental Parasitology 129(4), 402-8.

Fortes AM, Agudelo-Romero P, Silva MS, Ali K, Sousa L, Maltese F, Choi YH, Grimplet J, Martinez-Zapater JM, Verpoorte R, Pais MS (2011) Transcript and metabolite analysis in Trincadeira cultivar reveals novel information regarding the dynamics of grape ripening. BMC Plant Biology 11, 149. doi:10.1186/1471-2229-11-149.

Sá-Leão R, Pinto FR, Aguiar S, Nunes S, Carriço JA, Frazão N, Gonçalves-Sousa N, Melo-Cristino J, de Lencastre H, and Ramirez M (2011) Analysis of invasiveness of pneumococcal serotypes and clones circulating in Portugal before widespread use of conjugate vaccines revealing heterogeneous behavior of clones expressing the same serotype, J Clin Microbiol, 49,1369-75

Falé P.L.V., Madeira P.J.A, Florêncio M.H., Ascensão L., Serralheiro M.L.M. (2011) Function of Plectranthus barbatus herbal tea as neuronal acetylcholinesterase inhibitor, Food and Function 2: 130-136. doi: 10.1039/C0FO00070A

de Bettencourt A.M., Duarte M.F., Florêncio M.H., Henriques F.F., Madeira P.A., Portela M.I., Vilas-Boas L.F. (2011) Possible key intermediates in arsenic biochemistry: Synthesis and identification by liquid chromatography electrospray ionization mass spectrometry and high resolution mass spectrometry, Microchemical Journal, 99: 218-234 
 doi: 10.1016/j.microc.2011.05.007

2010

Barata, L., Sousa Silva, M., Schuldt, L., Tomás, A.M., Ferreira, A.E.N., Weiss, M.S., Ponces Freire, A., Cordeiro, C. (2010) Cloning, Expression, Purification, Crystallization and Preliminary X-ray Diffraction Analysis of Glyoxalase I from Leishmania infantum, Acta Crystallographica Section F 66, 571-4.

da Costa G,. Correia CF, Gomes RJ, Freire A, Monteiro E, Barroso E, Coelho AV , Outeiro TF, Freire AP and Cordeiro C. (2010) A non-invasive method based on saliva to characterize TTR in PAF patients using FT-ICR high-resolution mass spectrometry, Proteomics Clin. Appl. 4, 674-8.

Lamy E, da Costa G, Santos R, Capela E Silva F, Potes J, Pereira A, Coelho AV, Sales Baptista E. (2010) Effect of condensed tannin ingestion in sheep and goat parotid saliva proteome, J Anim Physiol Anim Nutr (Berl), doi: 10.1111/j.1439-0396.2010.01055.x.

Lamy E, Graca G, da Costa G, Franco C, Capela E Silva F, Sales Baptista E, Coelho AV. (2010) Changes in mice whole saliva soluble proteome induced by tannin-enriched diets, Proteome Science, 15;8(1), 65.

Oliveira BL, Raposinho PD, Mendes F, Santos IC, Santos IS, Ferreira A, Cordeiro C, Freire AP, Correia JDC (2010) Targeting nitric oxide synthase with 99mTc/Re tricarbonyl complexes containing pendant guanidino or isothiourea moieties, Journal of Organometalic Chemistry, doi:10.1016/j.jorganchem.2010.09.019.

Oliveira BL, Raposinho PD, Mendes F, Figueira A, Santos I, Ferreira A, Cordeiro C, Freire AP, Correia JD (2010) Re and Tc Tricarbonyl Complexes: From the Suppression of NO Biosynthesis in Macrophages to in Vivo Targeting of Inducible Nitric Oxide Synthase, Bioconjugate Chemistry, 21(12), 2168-72.

Carrolo M, Frias MJ, Pinto FR, Melo-Cristino J, Ramirez M. (2010) Prophage Spontaneous Activation Promotes DNA Release Enhancing Biofilm Formation in Streptococcus pneumoniae, PLoS One 5(12), e15678.

Aguiar SI, Pinto FR, Nunes S, Serrano I, Melo-Cristino J, Sá-Leão R, Ramirez M, de Lencastre H (2010) Increase of Denmark14-230 clone as a cause of pneumococcal infection in Portugal within a background of diverse serotype 19A lineages, Journal of Clinical Microbiology, 48(1), 101-8.

Madeira P.J.A., Xavier N.M., Rauter A.P., Florêncio M.H. (2010) Furanose C-C-linked γ-lactones: a combined ESI FTICR MS and semi-empirical calculations study. Journal of Mass Spectrometry, 45: 1167-1178. doi: 10.1002/jms.1806
Saraiva M.A., Borges C.M., Florêncio M.H. (2010) Behaviour of 4-(-2-hydroxyethyl)-1-piperazineethanesulfonic acid under electrospray ionization mass spectrometry conditions, European Journal of Mass Spectrometry, 16: 199-213. doi: 10.1255/ejms.

Madeira P.J.A., Rosa A.M., Xavier N.M., Rauter A.P., Florêncio M.H. (2010), Electrospray ionization mass spectrometric analysis of newly synthesised a,b-unsaturated g-lactones fused to sugars, Rapid Communications in Mass Spectrometry, 24: 1049–1058. doi: 10.1002/rcm.4490
 
Porfírio S., Falé P.L., Madeira P.J.A., Florêncio M.H., Ascensão L., Serralheiro M.L.M (2010), Antiacetylcholinesterase and antioxidant activities of Plectranthus barbatus tea, after in-vitro gastrointestinal metabolismo, Food Chemistry, 122: 179-187. doi: 10.1016/j.foodchem.2010.02.044

Madeira P.A., Borges C.M., Florêncio M.H. (2010) Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometric and semi-empirical calculations study of five isoflavone aglycones, Rapid Communications in Mass Spectrometry, 24: 3432–3440. doi: 10.1002/rcm.4791


2009

R. Santos, G. da Costa, C. Franco, P. Alves, P. Flammang and A. V. Coelho (2009) First insights into the biochemistry of tube foot adhesives from the sea urchin Paracentrotus lividus, Marine Biotechnol, 11, 686-98.

Toubarro, D., M. Lucena-Robles, G. Nascimento, da Costa G., R. Montiel, A. Coelho, N. Simões (2009) An apoptosis induncing serine protease secreted by the entomopathogenic nematode Steinernema caopocapsa, Int J Parasitol., 39, 1319-30.

Chaves I, Pinheiro C, Paiva JAP, Planchon S, Sergeant K, Renaut J, JGraça JA, da Costa G, Coelho AV, Ricardo CPP (2009) Proteomic evaluation of wound-healing processes in Potato (Solanum tuberosum L.) tuber tissue. Proteomics, 9, 4154-75.

Campos A, da Costa G, Coelho AV and Fevereiro P (2009) Identification of bacterial protein markers and enolase as a plant response protein to infection of Olea europaea L. subsp. europaea by Pseudomonas savastanoi pv savastanoi. Eur J Plant Pathol, 125, 603-16.

Lamy, E., G. Da Costa, R. Santos, F. Capela e Silva, J. Potes, A. Pereira, A.V. Coelho A and E. Sales Baptista (2009) Sheep and goat saliva proteome analysis: a useful tool for ingestive behavior research?, Physiol Behav, 98, 393-40.
Pinto F.R.J (2009) A Probabilistic Approach to Study Yeast’s Gene Regulatory Network. Comput Sci Syst Biol, 2, 044-050.

Carrolo M, Pinto FR, Melo-Cristino J, Ramirez M, (2009) Pherotypes are driving genetic differentiation within Streptococcus pneumonia. BMC Microbiol., 9, 191.

da Costa G, Gomes R, Correia CF, Freire A, Monteiro E, Martins A, Barroso E, Coelho AV, Outeiro TF, Ponces Freire A, Cordeiro C.(2009) Identification and quantitative analysis of human transthyretin variants in human serum by Fourier transform ion-cyclotron resonance mass spectrometry. Amyloid. 16, 201-207.

Faria D, Ferreira AE, Falcão AO (2009) Enzyme classification with peptide programs: a comparative study. BMC Bioinformatics, 24, 231

Oliveira B.L., Correia J.D., Raposinho P.D., Santos I., Ferreira A., Cordeiro C., Freire A.P. (2009) Re and 99mTc organometallic complexes containing pendant l-arginine derivatives as potential probes of inducible nitric oxide synthase. Dalton Transactions. Jan 7, 1: 152-162

Justino G.C., Borges C.M., Florêncio M.H. (2009) Electrospray ionization tandem mass spectrometry fragmentation of protonated flavone and flavonolaglycones: a re-examination”, Rapid Communications in Mass Spectrometry, 23: 237–248. doi: 10.1002/rcm.3869

Amaral S., Mira L., Nogueira J.M.F., da Silva A.P., Florêncio M.H. (2009) Plant extracts with anti-inflammatory properties – A new approach for characterization of their bioactive compounds and establishment of structure-antioxidant activity relationships, Bioorganic & Medicinal Chemistry, 17: 1876-1883. doi: 10.1016/j.bmc.2009.01.045.

Falé P.L., Borges C., Madeira P.J.A., Ascensão L., Araújo M.E.M., Florêncio M.H., Serralheiro M.L.M. (2009) Rosmarinic acid, scutellarein 40-methyl ether 7-O-glucuronide and (16S)-coleon E are themain compounds responsible for the antiacetylcholin esterase and antioxidant activity in herbal tea of Plectranthus barbatus (‘‘falso boldo”), Food Chemistry, 114: 798-805. doi: 10.1016/j.foodchem.2008.10.015

Xavier N.M., Madeira P.J.A., Florêncio M.H., Rauter A.P. (2009) Synthetic Approaches to Novel Thiosugar Scaffolds Containing a,b-Unsaturated Carbonyl Groups, European Journal of Organic Chemistry, 4983-4991 doi: 10.1002/ejoc.200900573
Madeira P.J.A., Florêncio M.H. (2009) Flavonoid-Matrix cluster ions in MALDI Mass Spectrometry, Journal of Mass Spectrometry, 44: 1105-1113. doi: 10.1002/jms.1588

Justino G.C., Rodrigues M., Florêncio M.H., Mira L. (2009) “Structure and antioxidant activity of brominated flavonols and flavanones”, Journal of Mass Spectrometry, 44: 1459–1468. doi: 10.1002/jms.1630

Castro A.L., Nunes M.R., Carvalho M.D., Ferreira L.P., Jumas J.-C., Costa F.M., Florêncio M.H. (2009) Doped titanium dioxide nanocrystalline powders with high photocatalytic activity, Journal of Solid State Chemistry, 182: 1838-1845 doi: 10.1021/cm0351238

2008

Pinto F.R., Melo-Cristino J., Ramirez M. (2008) A Confidence Interval for the Wallace Coefficient of Concordance and Its Application to Microbial Typing Methods. PLoS ONE, 3(11):e3696. doi:10.1371/journal.pone.0003696

Fortes A.M., Santos F., Choi Y.H., Silva M.S., Figueiredo A., Sousa L., Pessoa F., Santos B.A., Sebastiana M., Palme K., Malhó R., Verpoorte R., Pais M.S. (2008) Organogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses. BMC Genomics. 9: 445.

Gomes R.A, Oliveira L.M., Silva M., Ascenso C, Quintas A., Costa G., Coelho A.V., Sousa Silva M., Ferreira A.E., Ponces Freire A., Cordeiro C.(2008) Protein glycation in vivo: functional and structural effects on yeast enolase. Biochem J, 416: 317-326.

Sousa Silva, M., Barata, L., Ferreira, A.E.N., Romão, S., Tomás, A.M., Ponces Freire, A., Cordeiro, C. (2008) Catalysis and Structural Properties of Leishmania infantum Glyoxalase II: Trypanothione Specificity and Phylogeny, Biochemistry, 47: 195-204. DOI: 10.1021/bi700989m.

Vicente Miranda, H. , Ferreira, A.E.N., Quintas, A., Cordeiro, C., Ponces Freire, A. (2008) Measuring Intracellular Enzyme Concentrations. Biochemical and Molecular Biology Education, 36:135-138.

Ispolnov K., Gomes R.A., Silva M.S., Freire A.P. (2008) Extracellular methylglyoxal toxicity in Saccharomyces cerevisiae: role of glucose and phosphate ions. Journal of Applied Microbiology, 104: 1092-1102.

Gomes, R., Vicente Miranda, H., Sousa Silva, M., Graça, G., Coelho, A. V., Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2008) Protein glycation and methylglyoxal metabolism in yeast: finding peptide needles in protein haystacks. FEMS Yeast Research, 8: 174-181. 

Santos, M.R., Rodriguez-Gomez, M.J., Justino, G.C., Charro, N., Florencio, M.H., Mira, L. (2008) Influence of the metabolic profile on the in vivo antioxidant activity of quercetin under a low dosage oral regimen in rats. Brazilian Journal of Pharmacology 153: 1750-1761. doi: 10.1038/bjp.2008.46

Castro, A.L., Madeira, P.J., Nunes, M.R., Costa, F.M., Florencio, M.H. (2008) Titanium dioxide anatase as matrix for matrix-assisted laser desorption/ionization analysis of small molecules. Rapid Communications in Mass Spectrometry 22: 3761-3766. doi: 10.1002/rcm.3789

Castro A.L., Nunes M.R., Carvalho A.P., Costa F.M., Florêncio M.H. (2008) Synthesis of anatase TiO2 nanoparticles with high temperature stability and photocatalytic activity”, Solid State Sciences, Solid State Sciences, 10: 602-606 doi: 10.1016/j.solidstatesciences.2007.10.012

Xavier N.M., Silva S., Madeira P.J.A., Florêncio M.H., Silva F.V.M., Justino J., Thiem J., Rauter A.P. (2008) Synthesis and Biological Evaluation of Sugars Containing α,β-Unsaturated γ-Lactones, European Journal of Organic Chemistry, 6134-6143. doi: 10.1002/ejoc.200800763 

2007 and before

Neng, N.R., Cordeiro,C., Ponces Freire, A., Nogueira, J.M.F. (2007) Determination of glyoxal and methylglyoxal in environmental and biological matrices by stir bar sorptive extraction with in situ derivatization. Journal of Cromatography A, 1169: 47-52.

Almeida, C., Serodio, P., Florencio, M.H., Nogueira, J.M. (2007) New strategies to screen for endocrine-disrupting chemicals in the Portuguese marine environment utilizing large volume injection-capillary gas chromatography-mass spectrometry combined with retention time locking libraries (LVI-GC-MS-RTL). Analytical Bioanalytical Chemistry 387: 2569-2583. doi: 10.1007/s00216-006-1101-2

Farinha, C.M., Ponces Freire, A. (2007) Teaching biochemistry at Lisbon University – Facing the challenge of the Bologna Declaration in the 25th anniversary of the biochemistry course. Biochemical and Molecular Biology Education, 35: 422-424.

Oliveira, L.M.A., Cordeiro, C., Ponces Freire, A., Ascenso, C., Quintas, A. (2007) Unveiling heme proteins conformational stability through a UV absorbance ratio method. Analytical Biochemistry, 371: 253-255. abstract

Maia, L., Duarte, R., Moura, J., Ponces Freire, A., Mira, L. (2007) NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production. Journal of Biological Inorganic Chemistry, 12: 777-787.

Gomes, R., Vicente Miranda, H., Sousa Silva, M., Graça, G., Coelho, A. V., Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2006) Yeast protein glycation in vivo by methylglyoxal Molecular modification of glycolytic enzymes and heat shock proteins. FEBS Journal, 273: 5273-5287

Saraiva, M.A., Borges, C.M., Florencio, M.H. (2006) Towards the control and inhibition of glycation-the role of the guanidine reaction center with aldehydic and diketonic dicarbonyls. A mass spectrometry study. Journal of Mass Spectrometry 41: 1346-1368.

Saraiva, M.A., Borges, C.M., Florencio, M.H. (2006) Non-enzymatic model glycation reactions--a comprehensive study of the reactivity of a modified arginine with aldehydic and diketonic dicarbonyl compounds by electrospray mass spectrometry. Journal of Mass Spectrometry 41: 755-770. 

Saraiva, M.A., Borges, C.M., Florencio, M.H. (2006) Reactions of a modified lysine with aldehydic and diketonic dicarbonyl compounds: an electrospray mass spectrometry structure/activity study. Journal of Mass Spectrometry 41: 216-228. 

Trincão J., Sousa Silva M., Barata L., Bonifacio C., Carvalho S., Tomas A.M., Ferreira, A.E.N., Cordeiro C., Ponces Freire A., Romao M.J. (2006) Purification, crystallization and preliminary X-ray diffraction analysis of the glyoxalase II from Leishmania infantum. Acta Crystallograph Sect F Struct Biol Cryst Commun. 62: 805-807

Vicente Miranda, H. , Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2005) Kinetic assay for measurement of enzyme concentration in situ. Analytical Biochemistry, 354: 148-150.

Gomes, R., Sousa Silva, M., Vicente Miranda, H. , Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2005) Protein glycation in Saccharomyces cerevisiae : Argpyrimidine formation and methylglyoxal catabolism. FEBS Journal , 272(17): 4521-4531.

Abecasis, J.P.R., Ferreira, A.E.N., Vicente Miranda, H. , Gomes, R., Sousa Silva, M., Cordeiro, C., Ponces Freire, A. (2005) Parameter estimation in multi-enzyme systems using evolutionary algorithms. BKDB2005 – Bioinformatics: Knowledge Discovery in Biology . Faculdade de Ciências de Lisboa Ed. pp 48-52.

Sousa Silva, M. , Ferreira, A.E.N., Tomás, A.M., Cordeiro, C., Ponces Freire, A. (2005) Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation. FEBS Journal 272(10): 2388-2398.

do Rosario PM , Cordeiro CA , Freire AP , Nogueira JM (2005) Analysis of methylglyoxal in water and biological matrices by capillary zone electrophoresis with diode array detection. Electrophoresis, 26(9):1760-1767.

Gomes, R., Sousa Silva, M. , Quintas, A., Cordeiro, C., Freire, A., Pereira, P., Martins, A., Monteiro, E., Barroso, E., Ponces Freire, A. (2005) Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy. Biochemical Journal 385: 339-345

Vicente Miranda, H. , Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2005) Kinetic assay for measurement of enzyme concentration in situ. Analytical Biochemistry, 354:148-150.

Gomes, R., Sousa Silva, M., Vicente Miranda, H. , Ferreira, A.E.N., Cordeiro, C., Ponces Freire, A. (2005) Protein glycation in Saccharomyces cerevisiae : Argpyrimidine formation and methylglyoxal catabolism. FEBS Journal , 272(17): 4521-4531.  

Abecasis, J.P.R., Ferreira, A.E.N., Vicente Miranda, H. , Gomes, R., Sousa Silva, M., Cordeiro, C., Ponces Freire, A. (2005) Parameter estimation in multi-enzyme systems using evolutionary algorithms. BKDB2005 – Bioinformatics: Knowledge Discovery in Biology . Faculdade de Ciências de Lisboa Ed. pp 48-52.

Sousa Silva, M. , Ferreira, A.E.N., Tomás, A.M., Cordeiro, C., Ponces Freire, A. (2005) Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation. FEBS Journal 272(10): 2388-2398.

Madeira, P., Nunes, M.R., Borges, C., Costa, F.M., Florencio, M.H. (2005) Benzidine photodegradation: a mass spectrometry and UV spectroscopy combined study. Rapid Communications in Mass Spectrometry 19: 2015-2020. doi: 10.1002/rcm.2019

do Rosario PM , Cordeiro CA , Freire AP , Nogueira JM (2005) Analysis of methylglyoxal in water and biological matrices by capillary zone electrophoresis with diode array detection. Electrophoresis, 26(9):1760-1767.  

Gomes, R., Sousa Silva, M. , Quintas, A., Cordeiro, C., Freire, A., Pereira, P., Martins, A., Monteiro, E., Barroso, E., Ponces Freire, A. (2005) Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy. Biochemical Journal 385: 339-345.

Florencio, M.H., Pires, E., Castro, A.L., Nunes, M.R., Borges, C., Costa, F.M. (2004) Photodegradation of Diquat and Paraquat in aqueous solutions by titanium dioxide: evolution of degradation reactions and characterisation of intermediates. Chemosphere 55: 345-355. doi: 10.1016/j.chemosphere.2003.11.013

Justino, G.C., Santos, M.R., Canario, S., Borges, C., Florencio, M.H., Mira, L. (2004) Plasma quercetin metabolites: structure-antioxidant activity relationships. Arch Biochem Biophys 432: 109-121. doi: 10.1016/j.abb.2004.09.007

Ponces-Freire, A., Ferreira, A.E., Gomes, R. and Cordeiro, C. (2003) Antiglycation defences in yeast. Biochem. Soc. Trans. 31 : 1409-1412. 

Nogueira J.M.F., Simplício B., Florêncio M.H., Bettencourt A.M.M. (2003) Levels of Tributyltin in Sediments from Tagus Estuary Nature Reserve. Estuaries, 2003, 26: 310-314. doi: 10.1007/Bf02711990

Ferreira, A.E., Ponces-Freire, A. and Voit, E.O. (2003) A quantitative model of the generation of N-e-carboxymethyl-lysine in the Maillard reaction between collagen and glucose. Biochemical J. 376 : 109-121.

Fernandez M.T., Mira M.L., Florêncio M.H., Jennings K.R. (2002) Iron and Copper Chelation by Flavonoids- An Electrospray Mass Spectrometry Study, Journal of Inorganic Biochemistry, 92: 105-111. doi: 10.1016/S0162-0134(02)00511-1

Mira M.L., Fernandez M.T., Santos M., Rocha R., Florêncio M.H., Jennings K.R. (2002) Interactions of Flavonoids with Iron and Copper Ions: A Mechanism for their Antioxidant Activity, Free Radical Research, 36: 1199-1208. doi: 10.1016/j.aca.2008.04.033.

Janosik T., Bergman J., Romero I., Stensland B., Stalhandske C., Marques M.M.B., Santos M.M.M., Lobo A.M., Prabhakar S., Duarte M.F., Florêncio M.H. (2002) Synthetic, spectroscopic and X-ray crystallographic studies of [1,2,7,8]tetra thiacyclododecino[4,3-b:5,6-b´:10,9-b´´:11,12-b´´´]tetraindoles, European Journal of Organic Chemistry, 1392-1396. doi: 10.1002/1099-0690(200204)2002:8<1392::AID-EJOC1392>3.0.CO;2-#

Ahmed, N., Argirov, O., Minhas, H., Cordeiro, C. and Thornaley, P.J. (2002) Assay of advanced glycation endproducts (AGEs) by chromatographic assay with derivatisation by aminoquinolyl-N-hydroxysuccinimidyl-carbamate and application to N-e-carboxymethyl-lysine- and N-e-(1-carboxyethyl)lysine-modified albumin, Biochem. J. 364 : 1-14. 

Moiteiro C., Justino F., Tavares R., Marcelo-Curto M.J., Florêncio M.H., Nascimento M.S.J., Pedro M., Cerqueira F., Pinto M.M.M. (2001), Synthetic Seco-Friedelane and Friedelane Derivatives as Inhibitors of Human Lymphocyte Proliferation and Growth of Human Cancer Cell Lines in Vitro, Journal of Natural Products 64: 1273-1277. doi 10.1021/np010217m

Larsen B.R., Astorga-Llorens C., Florêncio M.H., Bettencourt A.M. (2001) Fragmentation Pathways of Organoarsenical Compounds by Electrospray Ion Trap Multiple Mass Spectrometry (MS6), Journal of Chromatography A, 926: 167-174. doi: 10.1016/S0021-9673(01)00905-0

Nogueira J.M.F.,Teixeira P., Florêncio M.H. (2001) Optimization and Validation of Tributyltin by SPE/CGC/MSD, Journal Microcolumn Separations, 13: 48-53. doi: 10.1002/mcs.1020

Martins, A., Mendes, P., Cordeiro, C. and Ponces Freire, A. (2001) In situ kinetic analysis of glyoxalase I and glyoxalase II in Saccharomyces cerevisiae, Eur. J. Biochem. 268 : 3930-3936.

Martins, A., Cordeiro, C. and Ponces Freire, A. (2001) In situ analysis of methylglyoxal metabolism in Saccharomyces cerevisiae , FEBS Letters, 499: 41-44. 

Florêncio M. H., Fast Atom Bombardment (FAB) mass spectra: usual and unusual features, in New Advances in Analytical Chemistry (Atta-ur-Rahman Editor); Harwood Academic Publishers, Amsterdam, 2000; p 77-96.
 
Silva A.P., Rocha R., Silva C.L., Mira L., Duarte M.F., Florêncio M.H. (2000), Antioxidants in medicinal plant extracts. A research study of the antioxidant capacity of Crataegus, Hamamelis and Hydrastis. Physiotherapy Research, 14: 612-616. doi: 10.1002/1099-1573(200012)14:8<612::AID-PTR677>3.0.CO;2-T

Martins, A., Cordeiro, C. and Ponces Freire, A. (1999) Glyoxalase II in Saccharomyces cerevisiae: In situ kinetics using the 5,5′-dithiobis(2-nitrobenzoic) acid assay, Arch. Biochem. Biophys. 366 : 15-20.

Silva, C.M., Duarte, M.F., Mira, M.L., Florencio, M.H., Versluis, K., Heck, A.J. (1999) Copper and iron interactions with angiotensin-converting enzyme inhibitors. A study by fast-atom bombardment tandem mass spectrometry. Rapid Communications in Mass Spectrometry 13: 1098-1103. doi: 10.1002/(SICI)1097-0231(19990630)13:12<1098::AID-RCM618>3.0.CO;2-Y

Santos M.S.C.S., Florêncio M.H., Barbosa E.F.G. (1998) Silver (I) induced tertiary amine oxidation in toluene, Anales de Química, International Edition, 94: 88-93. SICI:1130-2283(1998) 94:2<88:SITAOI>2.0.ZU;2-X

Fernandez M.T., Silva M., Mira M.L., Florêncio M. H., Gill A.C., Jennings K. R. (1998), Iron and Copper Complexation by Angiotensin-converting Enzyme (ACE) Inhibitors. A study by Ultraviolet Spectroscopy and Electrospray Mass Spectrometry, Journal of Inorganic Biochemistry, 71: 93-98. doi: 10.1016/S0162-0134(98)10037-5

Florêncio M.H., Fernandez M. T., Mira M.L., Millar A., Jennings K.R. (1998), Electrospray Mass Spectrometry of Angiotensin-converting Enzyme (ACE) Inhibitors, Rapid Communications in Mass Spectrometry, 12: 1928-1932. doi: 10.1002/(SICI)1097-0231(19981215)12:23<1928::AID-RCM405>3.0.CO;2-W

Voit, E.O. and Ferreira, A. (1998) Buffering in Models of Integrated Biochemical Systems, J. Theor. Biol. , 268: 3930-3936.

de Bettencourt A.M.M., Duarte M.F., Facchetti S., Florêncio M.H., Gomes M.L., van´t Klooster H.A., Montanarella L., Ritsema R., Vilas Boas L.F. (1997) Evidence of the presence of dimethylated, trimethylated and "refractory" arsenic compounds in estuarine salt-marsh halophytes, Applied Organometallic Chemistry, 11: 439-450. doi: 10.1002/(SICI)1099-0739(199705)11:5<439:AID-AOC609>3.0.CO;2H

Florêncio M.H., Duarte M.F., de Bettencourt A.M.M., Gomes M.L., Vilas Boas L.F. (1997), Electrospray mass spectra of arsenic compounds, Rapid Communications in Mass Spectrometry, 11: 469-473. doi: 10.1002/(SICI)1097-0231(199703)11:5<469:AID-RCM831>3.0.CO;2-7

Florêncio M.H., Duarte M.F., Facchetti S., Gomes M.L., Goesser W., Irgolic K.J., van´t Klooster H.A., Montanarella L., Ritsema R., Vilas Boas L.F., de Bettencourt A.M.M. (1997) Identification of inorganic, methylated and hydride-refractory arsenic species in estuarine waters. Advances by electrospray, ES-MS, Pyrolysis-GC-MS and HPLC-ICP/MS, Analysis, 25: 226-229. Journal ISSN: o365-4877

Ramalho L.F., Prazeres A.O., Gigante B., Marcelo Curto M.J., Florêncio M.H. (1997) Intramolecular reactions. An explanation for [M-H]+ ions in the chemical ionization mass spectra of some ring C-substituted methyl dehydroabietate derivatives. Rapid Communications in Mass Spectrometry, 11: 1695-1698. doi: 10.1002/(SICI)1097-0231(19971015)11:153.0.CO;2-1

Cordeiro, C. and Ponces Freire, A. (1996) Methylglyoxal assay in cells as 2-methylquinoxaline using 1,2-diaminobenzene as derivatizing reagent, Anal. Biochem. 234 : 221-224.

Cordeiro, C. and Ponces Freire, A. (1996) Methylglyoxal, glyoxalase I and oxidative stress, Biochem. Soc. Transactions. 24 : 472S.

Cordeiro, C. and Ponces Freire, A. (1995) Digitonin permeabilization of Saccharomyces cerevisiae cells for in situ enzyme assay, Anal. Biochem. 229 . 145-148.

Florêncio M.H., Duarte M.F., de Bettencourt A.M.M. (1995) Optimization of fast atom bombardment, FAB, mass spectra of arsenobetaíne and arsenocholine , Applied Organometallic Chemistry, 9: 719-720. doi: 10.1002/aoc.590090811

Duarte M.F., Florêncio M.H. (1995) A Mass spectral investigation of ethylenediaminetetraacetic acid, European Journal Mass Spectrometry, 1: 51-57. doi: 10.1255/ejms.159

Santos A., Duarte M.F., Florêncio M.H., Saramago B. (1995) Effect of the surface tension of the matrix on the FAB mass spectral determination of ethylenediaminetetraacetic acid, Journal Chemical Society, Faraday Transactions, 91: 1203-1205. doi: 10.1039/FT9959101203

Ramalho L.F., Gigante B., Marcelo Curto M.J., Florêncio M.H. (1995) A fast atom bombardment mass spectrometry (FAB) study of diterpene resin acid derivatives , European Journal Mass Spectrometry, 1: 389-393. doi: 10.1255/ejms.123

Cordeiro, C. and Ponces Freire, A. (1994) Protein Determination in permeabilized yeast cells, Anal. Biochem. 223 . 321-323.

de Bettencourt A.M.M., Florêncio M.H., Duarte M.F.N., Gomes M.L.R., Vilas Boas L.F. (1994) Refractory methylated arsenic compounds in estuarine waters: tracing back elusive species?, Applied Organometallic Chemistry, 8: 43-56. doi: 10.1002/aoc.590080109

Despeyroux D., Jennings K.R., Florêncio M.H. (1994) Collision gas effects in the collision induced decomposition (CID) of protonated and cationized molecules of carbohydrate antibiotics, Organic Mass Spectrometry, 29: 483-490. doi: 10.1002/oms.1210290907

Florêncio M.H., Heerma W. (1993) Behaviour of methyl red under FAB conditions , Organic Mass Spectrometry, 28: 657-664. doi: 10.1002/oms.1210280602

Schröder D., Florêncio M.H., Zummack W., Schwarz H. (1992) Highly selective benzylic C-H bond activation of toluene by ´bar´ FeO+ in the gas phase , Helvetica Chimica Acta, 75: 1792-1797. doi: 10.1002/hlca.19920750605

Zappey H., Fokkens R.H., Ingemann S.I., Nibbering, Florêncio M.H. (1991) Site of gas-phase methylation of 1-phenyl-2-aminopropane, Organic Mass Spectrometry, 26: 587-594. doi: 10.1002/oms.1210260610

Egsgaard H., Carlsen L., Florêncio M.H., Drewello T., Schwarz H. (1989) Aci-Nitromethane-generated and characterized by Neutralization-Reionization Mass Spectrometry, Berichte der Bunsen-Gesellshaft für Physikalische Chemie, 93: 76-80. doi: 10.1002/bbpc.19890930115 

Address

Faculdade de Ciências da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa

Contacts

Email: cacordeiro@fc.ul.pt
Phone: +351-217500929

Links

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